Tag: Chemokine receptor

Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias

Yu-Chen Yen, Christopher T Schafer, Martin Gustavsson, Stefanie A Eberle, Pawel K Dominik, Dawid Deneka, Penglie Zhang, Thomas J Schall, Anthony A Kossiakoff, John J G Tesmer, Tracy M Handel

Sci Adv. 2022 Jul 15;8(28):eabn8063.

PMID: 35857509 PMCID: PMC9278869 DOI: 10.1126/sciadv.abn8063

Both CXC chemokine receptor 4 (CXCR4) and atypical chemokine receptor 3 (ACKR3) are activated by …

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