Tag: cryo-EM

Structural basis of lipopolysaccharide maturation by the O-antigen ligase

Khuram U. Ashraf, Rie Nygaard, Owen N. Vickery, Satchal K. Erramilli, Carmen M. Herrera, Thomas H. McConville, Vasileios I. Petrou, Sabrina I. Giacometti, Meagan Belcher Dufrisne, Kamil Nosol, Allen P. Zinkle, Chris L. B. Graham, Michael Loukeris, Brian Kloss, Karolina Skorupinska-Tudek, Ewa Swiezewska, David I. Roper, Oliver B. Clarke, Anne-Catrin Uhlemann, Anthony A. Kossiakoff, M. …

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Structures of ABCB4 provide insight into phosphatidylcholine translocation

Kamil Nosol, Rose Bang-Sørensen, Rossitza N Irobalieva, Satchal K Erramilli, Bruno Stieger, Anthony A Kossiakoff, Kaspar P Locher

Proc Natl Acad Sci USA 2021 Aug 17;118(33):e2106702118. 

PMID: 34385322 PMCID: PMC8379956 (available on 2022-02-12)

DOI: 10.1073/pnas.2106702118

ABCB4 is expressed in hepatocytes and translocates phosphatidylcholine into bile canaliculi. The mechanism of specific lipid recruitment from the canalicular …

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