Tag: immunotherapy

Protein Engineering: Advances in Phage Display for Basic Science and Medical Research

Elena K Davydova

Review Biochemistry (Mosc). 2022 Jan;87(Suppl 1):S146-S110

PMID: 35501993 PMCID: PMC8802281 DOI: 10.1134/S0006297922140127

Functional Protein Engineering became the hallmark of biomolecule manipulation in the new millennium, building on and surpassing the underlying structural DNA manipulation and recombination techniques developed and employed in the last decades of the 20th century. Because of their prominence …

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A T cell redirection platform for co-targeting dual antigens on solid tumors

Leonie Enderle, Karim H Shalaby, Maryna Gorelik, Alexander Weiss, Levi L Blazer, Marcin Paduch, Lia Cardarelli, Anthony Kossiakoff, Jarrett J Adams, Sachdev S Sidhu

MAbs. Jan-Dec 2021;13(1):1933690. doi: 10.1080/19420862.2021.1933690

PMID: 34190031

In order to direct T cells to specific features of solid cancer cells, we engineered a bispecific antibody format, named Dual Antigen T cell …

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