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Structural Modeling of Human Growth Hormone Receptor using Computational Simulations and NMR Spectroscopy

Rui H, Kossiakoff AA, Im W

Biophysical Journal, Volume 104, Issue 2, pp. 117a-118a


Much of multicellular biology depends on communication through extracellular signaling molecules that bind to membrane receptors and trigger intracellular signaling events and cell behaviors. One of the first paradigm systems for understanding how polypeptide hormones bind and activate their receptors was …

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