Tag: phosphatidylcholine

Structures of ABCB4 provide insight into phosphatidylcholine translocation

Kamil Nosol, Rose Bang-Sørensen, Rossitza N Irobalieva, Satchal K Erramilli, Bruno Stieger, Anthony A Kossiakoff, Kaspar P Locher

Proc Natl Acad Sci USA 2021 Aug 17;118(33):e2106702118. doi: 10.1073/pnas.2106702118.

PMID: 34385322 PMCID: PMC8379956 (available on 2022-02-12) DOI: 10.1073/pnas.2106702118

ABCB4 is expressed in hepatocytes and translocates phosphatidylcholine into bile canaliculi. The mechanism of specific lipid recruitment from the canalicular …

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