Tag: Enzyme mechanisms

Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase

Joël S Bloch, Alan John, Runyu Mao, Somnath Mukherjee, Jérémy Boilevin, Rossitza N Irobalieva, Tamis Darbre, Nichollas E Scott, Jean-Louis Reymond, Anthony A Kossiakoff, Ethan D Goddard-Borger, Kaspar P Locher

Nat Chem Biol. 2023 Jan 5

PMID: 36604564 DOI: 10.1038/s41589-022-01219-9

C-linked glycosylation is essential for the trafficking, folding and function of secretory and transmembrane proteins …

Continue reading