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142 entries « 1 of 8 »

Slezak, Tomasz; O'Leary, Kelly M; Li, Jinyang; Rohaim, Ahmed; Davydova, Elena K; Kossiakoff, Anthony A

Engineered protein G variants for multifunctional antibody-based assemblies Journal Article

In: Protein Sci, vol. 34, no. 2, pp. e70019, 2025, ISSN: 1469-896X.

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Engineered protein G variants for multifunctional antibody-based assemblies

Górniak, Ireneusz; Stephens, Zachery; Erramilli, Satchal K; Gawda, Tomasz; Kossiakoff, Anthony A; Zimmer, Jochen

Structural insights into translocation and tailored synthesis of hyaluronan Journal Article

In: Nat Struct Mol Biol, vol. 32, no. 1, pp. 161–171, 2025, ISSN: 1545-9985.

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Structural insights into translocation and tailored synthesis of hyaluronan

Kordon, Szymon P; Cechova, Kristina; Bandekar, Sumit J; Leon, Katherine; Dutka, Przemysław; Siffer, Gracie; Kossiakoff, Anthony A; Vafabakhsh, Reza; Araç, Demet

Conformational coupling between extracellular and transmembrane domains modulates holo-adhesion GPCR function Journal Article

In: Nat Commun, vol. 15, no. 1, pp. 10545, 2024, ISSN: 2041-1723.

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Conformational coupling between extracellular and transmembrane domains modulates holo-adhesion GPCR function

Ross, Philipp; Hilton, Hugo G; Lodwick, Jane; Slezak, Tomasz; Guethlein, Lisbeth A; McMurtrey, Curtis P; Han, Alex S; Nielsen, Morten; Yong, Daniel; Dulberger, Charles L; Nolan, Kristof T; Roy, Sobhan; Castro, Caitlin D; Hildebrand, William H; Zhao, Minglei; Kossiakoff, Anthony; Parham, Peter; Adams, Erin J

Molecular characterization of the archaic HLA-B*73:01 allele reveals presentation of a unique peptidome and skewed engagement by KIR2DL2 Journal Article

In: bioRxiv, 2024, ISSN: 2692-8205.

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Molecular characterization of the archaic HLA-B*73:01 allele reveals presentation of a unique peptidome and skewed engagement by KIR2DL2

Ogbu, Chinemerem P; Mandriota, Alexandria M; Liu, Xiangdong; de Las Alas, Mason; Kapoor, Srajan; Choudhury, Jagrity; Kossiakoff, Anthony A; Duffey, Michael E; Vecchio, Alex J

Biophysical Basis of Paracellular Barrier Modulation by a Pan-Claudin-Binding Molecule Journal Article

In: bioRxiv, 2024, ISSN: 2692-8205.

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Biophysical Basis of Paracellular Barrier Modulation by a Pan-Claudin-Binding Molecule

Rathnayake, Sewwandi S; Erramilli, Satchal K; Kossiakoff, Anthony A; Vecchio, Alex J

Cryo-EM structures of Clostridium perfringens enterotoxin bound to its human receptor, claudin-4 Journal Article

In: Structure, vol. 32, no. 11, pp. 1936–1951.e5, 2024, ISSN: 1878-4186.

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Cryo-EM structures of Clostridium perfringens enterotoxin bound to its human receptor, claudin-4

Liu, Yaqi; Brown, Chelsea M; Borges, Nuno; Nobre, Rodrigo N; Erramilli, Satchal; Dufrisne, Meagan Belcher; Kloss, Brian; Giacometti, Sabrina; Esteves, Ana M; Timoteo, Cristina G; Tokarz, Piotr; Cater, Rosemary; Morita, Yasu S; Kossiakoff, Anthony A; Santos, Helena; Stansfeld, Phillip J; Nygaard, Rie; Mancia, Filippo

Mechanistic studies of mycobacterial glycolipid biosynthesis by the mannosyltransferase PimE Journal Article

In: bioRxiv, 2024, ISSN: 2692-8205.

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Mechanistic studies of mycobacterial glycolipid biosynthesis by the mannosyltransferase PimE

Liu, Yaqi; Brown, Chelsea M; Erramilli, Satchal; Su, Yi-Chia; Tseng, Po-Sen; Wang, Yu-Jen; Duong, Nam Ha; Tokarz, Piotr; Kloss, Brian; Han, Cheng-Ruei; Chen, Hung-Yu; Rodrigues, Jose; Archer, Margarida; Lowary, Todd L; Kossiakoff, Anthony A; Stansfeld, Phillip J; Nygaard, Rie; Mancia, Filippo

Structural insights into terminal arabinosylation biosynthesis of the mycobacterial cell wall arabinan Journal Article

In: bioRxiv, 2024, ISSN: 2692-8205.

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Structural insights into terminal arabinosylation biosynthesis of the mycobacterial cell wall arabinan

Samassekou, Kadidia; Garland-Kuntz, Elisabeth E; Ohri, Vaani; Fisher, Isaac J; Erramilli, Satchal K; Muralidharan, Kaushik; Bogdan, Livia M; Gick, Abigail M; Kossiakoff, Anthony A; Lyon, Angeline M

Cryo-EM Structure of Phospholipase Cε Defines N-terminal Domains and their Roles in Activity Journal Article

In: bioRxiv, 2024, ISSN: 2692-8205.

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Cryo-EM Structure of Phospholipase Cε Defines N-terminal Domains and their Roles in Activity

Slezak, Tomasz; O'Leary, Kelly M; Li, Jinyang; Rohaim, Ahmed; Davydova, Elena K; Kossiakoff, Anthony A

Engineered Protein-G variants for plug-and-play applications Journal Article

In: bioRxiv, 2024, ISSN: 2692-8205.

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Engineered Protein-G variants for plug-and-play applications

Knejski, Paweł P; Erramilli, Satchal K; Kossiakoff, Anthony A

Chaperone-assisted cryo-EM structure of PhuR reveals molecular basis for heme binding Journal Article

In: bioRxiv, 2024, ISSN: 2692-8205.

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Chaperone-assisted cryo-EM structure of  PhuR reveals molecular basis for heme binding

Rathnayake, Sewwandi S; Erramilli, Satchal K; Kossiakoff, Anthony A; Vecchio, Alex J

Cryo-EM Structures of Clostridium perfringens Enterotoxin Bound to its Human Receptor, Claudin-4 Journal Article

In: bioRxiv, 2024, ISSN: 2692-8205.

Abstract | Links | BibTeX

Cryo-EM Structures of Clostridium perfringens Enterotoxin Bound to its Human Receptor, Claudin-4

Lan, Tong; Slezak, Tomasz; Pu, Jinyue; Zinkus-Boltz, Julia; Adhikari, Sarbani; Pekow, Joel R; Taneja, Vibha; Zuniga, Joaquin; Gómez-García, Itzel A; Regino-Zamarripa, Nora; Ahmed, Mushtaq; Khader, Shabaana A; Rubin, David T; Kossiakoff, Anthony A; Dickinson, Bryan C

Development of Luminescent Biosensors for Calprotectin Journal Article

In: ACS Chem Biol, vol. 19, no. 6, pp. 1250–1259, 2024, ISSN: 1554-8937.

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Development of Luminescent Biosensors for Calprotectin

Lodwick, Jane E; Shen, Rong; Erramilli, Satchal; Xie, Yuan; Roganowicz, Karolina; Kossiakoff, Anthony A; Zhao, Minglei

Structural Insights into the Roles of PARP4 and NAD in the Human Vault Cage Journal Article

In: bioRxiv, 2024, ISSN: 2692-8205.

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Structural Insights into the Roles of PARP4 and NAD  in the Human Vault Cage

Erramilli, Satchal K; Dominik, Pawel K; Ogbu, Chinemerem P; Kossiakoff, Anthony A; Vecchio, Alex J

Structural and biophysical insights into targeting of claudin-4 by a synthetic antibody fragment Journal Article

In: Commun Biol, vol. 7, no. 1, pp. 733, 2024, ISSN: 2399-3642.

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Structural and biophysical insights into targeting of claudin-4 by a synthetic antibody fragment

Cater, Rosemary J; Mukherjee, Dibyanti; Gil-Iturbe, Eva; Erramilli, Satchal K; Chen, Ting; Koo, Katie; Santander, Nicolás; Reckers, Andrew; Kloss, Brian; Gawda, Tomasz; Choy, Brendon C; Zhang, Zhening; Katewa, Aditya; Larpthaveesarp, Amara; Huang, Eric J; Mooney, Scott W J; Clarke, Oliver B; Yee, Sook Wah; Giacomini, Kathleen M; Kossiakoff, Anthony A; Quick, Matthias; Arnold, Thomas; Mancia, Filippo

Structural and molecular basis of choline uptake into the brain by FLVCR2 Journal Article

In: Nature, vol. 629, no. 8012, pp. 704–709, 2024, ISSN: 1476-4687.

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Structural and molecular basis of choline uptake into the brain by FLVCR2

Knejski, Paweł P; Erramilli, Satchal K; Kossiakoff, Anthony A

Chaperone-assisted cryo-EM structure of P. aeruginosa PhuR reveals molecular basis for heme binding Journal Article

In: Structure, vol. 32, no. 4, pp. 411–423.e6, 2024, ISSN: 1878-4186.

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Chaperone-assisted cryo-EM structure of P. aeruginosa PhuR reveals molecular basis for heme binding

Liu, Hongtao; Zakrzewicz, Dariusz; Nosol, Kamil; Irobalieva, Rossitza N; Mukherjee, Somnath; Bang-Sørensen, Rose; Goldmann, Nora; Kunz, Sebastian; Rossi, Lorenzo; Kossiakoff, Anthony A; Urban, Stephan; Glebe, Dieter; Geyer, Joachim; Locher, Kaspar P

Structure of antiviral drug bulevirtide bound to hepatitis B and D virus receptor protein NTCP Journal Article

In: Nat Commun, vol. 15, no. 1, pp. 2476, 2024, ISSN: 2041-1723.

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Structure of antiviral drug bulevirtide bound to hepatitis B and D virus receptor protein NTCP

Zhang, Lin; Duan, Hong-Chao; Paduch, Marcin; Hu, Jingyan; Zhang, Chi; Mu, Yajuan; Lin, Houwen; He, Chuan; Kossiakoff, Anthony A; Jia, Guifang; Zhang, Liang

The Molecular Basis of Human ALKBH3 Mediated RNA N -methyladenosine (m A) Demethylation Journal Article

In: Angew Chem Int Ed Engl, vol. 63, no. 7, pp. e202313900, 2024, ISSN: 1521-3773.

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The Molecular Basis of Human ALKBH3 Mediated RNA N -methyladenosine (m A) Demethylation

Kordon, Szymon P; Cechova, Kristina; Bandekar, Sumit J; Leon, Katherine; Dutka, Przemysław; Siffer, Gracie; Kossiakoff, Anthony A; Vafabakhsh, Reza; Araç, Demet

Structural analysis and conformational dynamics of a holo-adhesion GPCR reveal interplay between extracellular and transmembrane domains Journal Article

In: bioRxiv, 2024, ISSN: 2692-8205.

Abstract | Links | BibTeX

Structural analysis and conformational dynamics of a holo-adhesion GPCR reveal interplay between extracellular and transmembrane domains
142 entries « 1 of 8 »