David M Kern, Julia Bleier, Somnath Mukherjee, Jennifer M Hill, Anthony A Kossiakoff, Ehud Y Isacoff, Stephen G Brohawn
Nat Struct Mol Biol 2023 Mar 16
PMID: 36928458 DOI: 10.1038/s41594-023-00944-6
Leucine-rich repeat-containing protein 8 (LRRC8) family members form volume-regulated anion channels activated by hypoosmotic cell swelling. LRRC8 channels are ubiquitously expressed in vertebrate cells as …