Walsh ST, Jevitts LM, Sylvester JE, Kossiakoff AA
Protein Sci. 2003 Sep;12(9):1960-70
PMID: 12930995
Abstract
Receptor signaling in the growth hormone (GH)-growth hormone receptor (GHR) system is controlled through a sequential two-step hormone-induced dimerization of two copies of the extracellular domain (ECD) of the receptor. The regulatory step of this process is the binding of …