Kouadio JL, Horn JR, Pal G, Kossiakoff AA
J. Biol. Chem. 2005 Jul;280(27):25524-32
PMID: 15857837
Abstract
The high affinity binding site (Site1) of the human growth hormone (hGH) binds to its cognate receptor (hGHR) via a concave surface patch containing about 35 residues. Using 167 sequences from a shotgun alanine scanning analysis of Site1, we …